Bootstrap and MLS methods-based individual bioequivalence assessment
نویسندگان
چکیده
It is a one-sided hypothesis testing process for assessing bioequivalence. Bootstrap and modified large-sample(MLS) methods are considered to study individual bioequivalence(IBE), type I error and power of hypothesis tests are simulated and compared with FDA(2001). The results show that modified large-sample method is equivalent to the method of FDA(2001) . Keywords—individual bioequivalence; bootstrap; Bayesian bootstrap; modified large-sample
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